Ing. Ján Tkáč, DrSc.

chemik
Year of birth: 
1972
regular member
Year of joining: 
2017
Affiliation: 

Chemický ústav SAV

Phone: 
+421 2 5941 0263
Research interests: 
bionanotechnológie a glykomika
Top results: 

Štúdium využitia rôznych nanomateriálov alebo techník umožňujúcich kontrolu modifikácii povrchov v nanoškále pri príprave veľmi citlivých biočipov a ich následné využitie v diagnostike rozličných ochorení (najmä rôzne formy rakoviny) alebo v glykomike.

  1. Dosekova E, Filip J, Bertok T, Both P, Kasak P, Tkac J. Nanotechnology in glycomics: Applications in diagnostics, therapy, imaging, and separation Processes. Medicinal Research Reviews 2017;DOI: 10.1002/med.21420.
  2. Kveton F, Blšáková A, Hushegyi A, Damborsky P, Blixt O, Jansson B, Tkac J. Optimization of the small glycan presentation for binding a tumor-associated antibody: Application to the construction of an ultrasensitive glycan biosensor. Langmuir 2017;33:2709-2716.
  3. Pihikova D, Pakanova Z, Nemcovic M, Barath P, Belicky S, Bertok T, Kasak P, Mucha J, Tkac J. Sweet characterisation of prostate specific antigen using electrochemical lectin‐based immunosensor assay and MALDI TOF/TOF analysis: Focus on sialic acid. Proteomics 2016;16:3085-3095.
  4. Paleček E, Tkáč J, Bartošík M, Bertók Ts, Ostatná V, Paleček J. Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics. Chemical Reviews 2015;115:2045–2108.
  5. Hushegyi A, Bertok T, Damborsky P, Katrlík J, Tkac J. Ultrasensitive impedimetric glycan biosensor with controlled glycan density for detection of lectins and influenza hemagglutinins. Chemical Communications 2015;51:7474-7477.